Prurigo nodularis (PN) is a dermatological condition characterized by nodular hyperkeratotic lesions mainly on the legs and arms. Asymmetrical PN is a rare dermatological condition often associated with paralysis and stroke. In this paper, we present the case of a 77-year-old woman who developed post-ictal PN which responded to dupilumab, an anti-interleukin-4/13 drug approved for the management of AD, with an extreme reduction in itch sensation. Dupilumab and other therapies reducing Th2 inflammation may, in the future, become an alternative treatment for post-ictal pruritus/PN nonresponding to traditional therapies. Of course, larger studies will be necessary to confirm our case's findings.
Post-stroke asymmetric prurigo nodularis responding to dupilumab treatment. a case report / Sammarra, Ilaria; Bennardo, Luigi; Provenzano, Eugenio; Patruno, Cataldo; Nisticò, Steven Paul. - In: BRAIN SCIENCES. - ISSN 2076-3425. - 12:5(2022), p. 5. [10.3390/brainsci12050605]
Post-stroke asymmetric prurigo nodularis responding to dupilumab treatment. a case report
Nisticò, Steven Paul
2022
Abstract
Prurigo nodularis (PN) is a dermatological condition characterized by nodular hyperkeratotic lesions mainly on the legs and arms. Asymmetrical PN is a rare dermatological condition often associated with paralysis and stroke. In this paper, we present the case of a 77-year-old woman who developed post-ictal PN which responded to dupilumab, an anti-interleukin-4/13 drug approved for the management of AD, with an extreme reduction in itch sensation. Dupilumab and other therapies reducing Th2 inflammation may, in the future, become an alternative treatment for post-ictal pruritus/PN nonresponding to traditional therapies. Of course, larger studies will be necessary to confirm our case's findings.File | Dimensione | Formato | |
---|---|---|---|
Sammarra_Post-Stroke_2022.pdf
accesso aperto
Tipologia:
Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza:
Creative commons
Dimensione
1.63 MB
Formato
Adobe PDF
|
1.63 MB | Adobe PDF |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.